Revista Farmabiotec Número 8

MKT#22-156 LAL Reagent Conventional ACC’s PyroSmart NextGen ® First Generation Comparison Table LAL Reagent (rCR) Reagent Competitor (rFC) Reagent Sustainable Reagent (animal free) No  Horseshoe Crab Blood Free  Horseshoe Crab Blood Free Kinetic Assay Kinetic  Kinetic  No. Endpoint only Assay Setup Single step  Single step  No. rFC requires three reagents reconstitution reconstitution in a 1:4:5 ratio and a 10 min. pre-incubation step Same Standard Plate Reader Incubating plate or  Yes. Incubating plate or  No. Fluorescent tube reader at 405 nm tube reader at 405 nm reader required Derived From LAL  Yes. rCR is recombinant LAL  No. Based on Carcinoscorpius Limulus Amebocyte Lysate (LAL) or Tachypleus Amebocyte Lysate (CAL/TAL) Multi-step Cascade Pathway Yes  Yes  No Endotoxin Specific No  Endotoxin Specific  Endotoxin Specific       